They can only withstand so many erase/program cycles before the area of memory being written to fails and can longer store data. The other problem is that the flash memory itself will wear out eventually. A common number of mentioned on the Internet is 10,000 insertion/removals for an SD card, which means it'll last 27 years if you plug it in and pull it out once every day. Along with newer game cartridges they're probably manufactured to better stand up to repeated insertions and removals than those old game cartridges. In practice I've never heard of memory card failing this way. Do not do this, or do anything else to try to clean the memory cards, it will just make things worse. You may have heard stories of people blowing into their old Nintendo cartridges to get them to work. The first is that since they have metal contacts like cartridge games, these contacts can wear out from repeated use just like they did with cartridge games. However nothing lasts forever and there are two ways your memory cards could end failing through normal use, even if you take the utmost care of them. So they won't lose their saves the same way your old GameBoy cartridges did because they don't have batteries that can go dead. PlayStation and PlayStation 2 memory cards, along with the Memory Stick Duo cards used by the PSP, all use flash memory which is a form non-volatile memory that doesn't need power to maintain its state.

How can you edit ps2 game saves